Reliability of genomic prediction for German Holsteins using imputed genotypes from low-density chips
نویسندگان
چکیده
منابع مشابه
Accuracy of genomic prediction using low-density marker panels.
Genomic selection has been widely implemented in national and international genetic evaluation in the dairy cattle industry, because of its potential advantages over traditional selection methods and the availability of commercial high-density (HD) single nucleotide polymorphism (SNP) panels. However, this method may not be cost-effective for cow selection and for other livestock species, becau...
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The objective of this study was to quantify the accuracy achievable from imputing genotypes from a commercially available low-density marker panel (2730 single nucleotide polymorphisms (SNPs) following edits) to a commercially available higher density marker panel (51 602 SNPs following edits) in Holstein-Friesian cattle using Beagle, a freely available software package. A population of 764 Hol...
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The objective of the present study was to evaluate the predictive ability of direct genomic values for economically important dairy traits when genotypes at some single nucleotide polymorphism (SNP) loci were imputed rather than measured directly. Genotypic data consisted of 42,552 SNP genotypes for each of 1,762 Jersey sires. Phenotypic data consisted of predicted transmitting abilities (PTA) ...
متن کاملFrequentist tests of association for imputed genotypes
Servin and Matthews [17] proposed looking for associations between phenotypes and both typed and untyped SNPs, by using a reference panel to infer the alleles of the untyped SNPs. Since then, a number of GWA studies have reported p-values for both typed and untyped SNPs. However, results of Almeida et al [1] indicate that using imputed genotype data can lead to increased type I error. We discus...
متن کاملeffect of enlarging the number of reference population cows and imputed markers on reliability of genomic prediction in jersey breed
the objective of this study was to evaluate the potential gain in accuracy of predictions by imputing genotypes from a low-density marker panel (6640 marker with 10 replicates) to a medium-density marker panel in a simulated population of jersey cattle using fimpute software and also to evaluate the reliability of genomic estimate of breeding values (gebv) for milk yield (h2=0.40) and fertility...
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ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 2012
ISSN: 0022-0302
DOI: 10.3168/jds.2012-5466